Assay Detail
Binding
CHEMBL994101
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiporter activity in Escherichia coli K12 wild type EcNhaA H225R mutant assessed as effect on lithium chloride-induced pH changes by acridine orange fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.64 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL311074 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL311074 | — | IC50 | = | 2300.0 | nM | 5.64 |