Assay Detail
Functional
CHEMBL994106
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Cytotoxicity against human A549 cells after 72 hrs by XTT colorimetric assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antitumor compounds based on a natural product consensus pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.69 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL494107 | — | — | 1 | 8.89 |
| CHEMBL1242745 | PLADIENOLIDE B | — | 1 | 8.85 |
| CHEMBL493292 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL494107 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL1242745 | PLADIENOLIDE B | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL493292 | — | IC50 | = | 4650.0 | nM | 5.33 |