Assay Detail
Functional
CHEMBL994109
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Cytotoxicity against human MCF7 cells after 72 hrs by XTT colorimetric assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antitumor compounds based on a natural product consensus pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.93 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1242745 | PLADIENOLIDE B | — | 1 | 9.40 |
| CHEMBL494107 | — | — | 1 | 8.74 |
| CHEMBL493292 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1242745 | PLADIENOLIDE B | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL494107 | — | IC50 | = | 1.8 | nM | 8.74 |
| CHEMBL493292 | — | IC50 | = | 2290.0 | nM | 5.64 |