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Assay Detail

CHEMBL994193

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Binding
Inhibition of Zipk
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Death-associated protein kinase 3 (CHEMBL2468)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling.
Tong Y, Stewart KD, Thomas S, Przytulinska M, Johnson EF, Klinghofer V, Leverson J, McCall O, Soni NB, Luo Y, Lin NH, Sowin TJ, Giranda VL, Penning TD.
Bioorg Med Chem Lett (2008) 18 : 5206 -5208
PubMed 18790640 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.56 7.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL523823 1 7.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL523823 Ki = 27.3 nM 7.56