Assay Detail
Binding
CHEMBL994319
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human insulin receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.48 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23254 | PURVALANOL B | — | 1 | 5.66 |
| CHEMBL23327 | PURVALANOLA | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23254 | PURVALANOL B | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL23327 | PURVALANOLA | IC50 | = | 5000.0 | nM | 5.30 |