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Assay Detail

CHEMBL995404

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FGFR autophosphorylation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis of 1-(2,6-dichlorophenyl)-3-methylene-1,3-dihydro-indol-2-one derivatives and in vitro anticancer evaluation against SW620 colon cancer cell line.
Virsodia V, Manvar A, Upadhyay K, Loriya R, Karia D, Jaggi M, Singh A, Mukherjee R, Shaikh MS, Coutinho EC, Shah A.
Eur J Med Chem (2009) 44 : 1355 -1362
PubMed 18316139 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL315546 1 5.00
CHEMBL89363 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL315546 IC50 = 10000.0 nM 5.00
CHEMBL89363 IC50 = 10000.0 nM 5.00