Assay Detail
Binding
CHEMBL995694
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Inhibition of amidolytic activity of human recombinant soluble tissue factor/human factor 7a preincubated with factor 7a for 90 mins
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibitory activity of unsaturated fatty acids and anacardic acids toward soluble tissue factor-factor VIIa complex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.54 | 4.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8739 | LINOLENIC ACID | — | 1 | 4.72 |
| CHEMBL464982 | GAMOLENIC ACID | 3.0 | 1 | 4.70 |
| CHEMBL8659 | OLEIC ACID | 2.0 | 1 | 4.68 |
| CHEMBL267476 | LINOLEIC ACID | 2.0 | 1 | 4.52 |
| CHEMBL453509 | PALMITOLEIC ACID | — | 1 | 4.10 |
| CHEMBL124632 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8739 | LINOLENIC ACID | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL464982 | GAMOLENIC ACID | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL8659 | OLEIC ACID | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL267476 | LINOLEIC ACID | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL453509 | PALMITOLEIC ACID | IC50 | = | 80000.0 | nM | 4.10 |
| CHEMBL124632 | — | IC50 | > | 200000.0 | nM | - |