Assay Detail
Functional
CHEMBL996417
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Cytotoxicity against human KB cells
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic flavonoids and alpha-pyrones from Cryptocarya obovata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.41 | 5.52 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL452184 | OBOLACTONE | — | 1 | 5.52 |
| CHEMBL525213 | OBOCHALCOLACTONE | — | 1 | 5.30 |
| CHEMBL499963 | OBOFLAVANONE A | — | 1 | - |
| CHEMBL504055 | OBOFLAVANONE B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL452184 | OBOLACTONE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL525213 | OBOCHALCOLACTONE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL499963 | OBOFLAVANONE A | Activity | - | — | - | |
| CHEMBL504055 | OBOFLAVANONE B | Activity | - | — | - |