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Assay Detail

CHEMBL997069

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Src kinase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Proto-oncogene tyrosine-protein kinase Src (CHEMBL267)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

c-Src protein kinase inhibitors block assembly and maturation of dengue virus.
Chu JJ, Yang PL.
Proc Natl Acad Sci U S A (2007) 104 : 3520 -3525
PubMed 17360676 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL217092 SARACATINIB 3.0 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL217092 SARACATINIB IC50 = 1.0 nM 9.00