Assay Detail
Functional
CHEMBL997208
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MCF7 cells by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The regulation of inflammatory cytokine secretion in macrophage cell line by the chemical constituents of Rhus sylvestris.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.45 | 4.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL489760 | beta-AMYRIN ACETATE | — | 1 | 4.57 |
| CHEMBL495810 | — | — | 1 | 4.51 |
| CHEMBL221542 | BETA-SITOSTEROL | — | 1 | 4.38 |
| CHEMBL229907 | — | — | 1 | 4.34 |
| CHEMBL496007 | — | — | 1 | - |
| CHEMBL495598 | — | — | 1 | - |
| CHEMBL289191 | LUPEOL | — | 1 | - |
| CHEMBL455098 | beta-AMYRIN | — | 1 | - |
| CHEMBL452242 | GLUTINOL | — | 1 | - |
| CHEMBL497823 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL489760 | beta-AMYRIN ACETATE | IC50 | = | 26730.0 | nM | 4.57 |
| CHEMBL495810 | — | IC50 | = | 30910.0 | nM | 4.51 |
| CHEMBL221542 | BETA-SITOSTEROL | IC50 | = | 42100.0 | nM | 4.38 |
| CHEMBL229907 | — | IC50 | = | 45390.0 | nM | 4.34 |
| CHEMBL496007 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL495598 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL289191 | LUPEOL | IC50 | > | 50000.0 | nM | - |
| CHEMBL455098 | beta-AMYRIN | IC50 | > | 50000.0 | nM | - |
| CHEMBL452242 | GLUTINOL | IC50 | > | 50000.0 | nM | - |
| CHEMBL497823 | — | IC50 | > | 50000.0 | nM | - |