Assay Detail
Functional
CHEMBL997216
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Cytotoxicity against human LAMA-84 cells after 48 hrs by Alamar Blue assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LAMA-84 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Efficient chemoenzymatic synthesis, cytotoxic evaluation, and SAR of epoxysterols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.30 | 6.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.12 |
| CHEMBL497835 | — | — | 1 | 5.39 |
| CHEMBL497834 | — | — | 1 | 5.32 |
| CHEMBL497816 | — | — | 1 | 5.16 |
| CHEMBL496805 | — | — | 1 | 5.10 |
| CHEMBL501171 | — | — | 1 | 5.09 |
| CHEMBL496407 | — | — | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 760.0 | nM | 6.12 |
| CHEMBL497835 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL497834 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL497816 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL496805 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL501171 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL496407 | — | IC50 | = | 11200.0 | nM | 4.95 |