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Assay Detail

CHEMBL997332

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Functional
Antioxidant activity assessed as DPPH radical scavenging activity by TLC autographic assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Constituents of the leaves of Macaranga tanarius.
Phommart S, Sutthivaiyakit P, Chimnoi N, Ruchirawat S, Sutthivaiyakit S.
J Nat Prod (2005) 68 : 927 -930
PubMed 15974621 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 8 4.71 4.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL464364 NYMPHAEOL B 1 4.89
CHEMBL223256 NYMPHAEOL A 1 4.85
CHEMBL455860 NYMPHAEOL C 1 4.82
CHEMBL499116 TANARIFLAVANONE D 1 4.70
CHEMBL146 BUTYLATED HYDROXYTOLUENE 2.0 1 4.52
CHEMBL518874 TANARIFLAVANONE C 1 4.48
CHEMBL457816 1 -
CHEMBL462919 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL464364 NYMPHAEOL B IC50 = 13000.0 nM 4.89
CHEMBL223256 NYMPHAEOL A IC50 = 14000.0 nM 4.85
CHEMBL455860 NYMPHAEOL C IC50 = 15000.0 nM 4.82
CHEMBL499116 TANARIFLAVANONE D IC50 = 20000.0 nM 4.70
CHEMBL146 BUTYLATED HYDROXYTOLUENE IC50 = 30000.0 nM 4.52
CHEMBL518874 TANARIFLAVANONE C IC50 = 33000.0 nM 4.48
CHEMBL457816 IC50 = 599000.0 nM -
CHEMBL462919 IC50 = 413000.0 nM -