Assay Detail
Functional
CHEMBL997469
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Antiproliferative activity against human CA46 cells after 24 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CA46 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.41 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL505302 | HECTOCHLORIN | — | 1 | 7.70 |
| CHEMBL257166 | JASPAMIDE | — | 1 | 7.52 |
| CHEMBL508049 | LYNGBYABELLIN B | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL505302 | HECTOCHLORIN | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL257166 | JASPAMIDE | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL508049 | LYNGBYABELLIN B | IC50 | = | 100.0 | nM | 7.00 |