Assay Detail
Binding
CHEMBL998079
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of 11beta-HSD1 in monkey hepatocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Macaca mulatta |
| Cell Type | Hepatocyte |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Hydroxysteroid 11-beta dehydrogenase 1 (CHEMBL5227) ↗| Type | SINGLE PROTEIN |
| Organism | Macaca mulatta |
Publication
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL495841 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL495841 | — | EC50 | = | 100.0 | nM | 7.00 |