Assay Detail

CHEMBL998375

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Functional

Cytotoxicity against mouse L1210 cells after 24 hrs

ChEMBL ↗

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Target

L1210 (CHEMBL386) ↗

Open DB target context

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Primary target L1210

CHEMBL386

Anchored from Assay target.

Protein identity L1210

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Cell Type	L1210
Confidence	1 — Organism
Curated By	Autocuration

Target

L1210 (CHEMBL386) ↗

Type	CELL-LINE
Organism	Mus musculus

Publication

Two new cytotoxic chalcones from Calythropsis aurea.

Beutler JA, Cardellina JH, Gray GN, Prather TR, Shoemaker RH, Boyd MR, Lin CM, Hamel E, Cragg GM.
J Nat Prod (1993) 56 : 1718 -1722
PubMed 8277311 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.16	5.16

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL340244	CALYTHROPSIN	—	1	5.16

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL340244	CALYTHROPSIN	IC50	=	7000.0	nM	5.16