Assay Detail
Functional
CHEMBL998455
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Cytotoxicity against human Caki1 cells after 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CAKI-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cucurbitane triterpenoids from Leucopaxillus gentianeus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.84 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507237 | CUCURBITACIN B | — | 1 | 5.15 |
| CHEMBL506664 | LEUCOPAXILLONE B | — | 1 | 4.52 |
| CHEMBL510964 | LEUCOPAXILLONE A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507237 | CUCURBITACIN B | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL506664 | LEUCOPAXILLONE B | IC50 | = | 30300.0 | nM | 4.52 |
| CHEMBL510964 | LEUCOPAXILLONE A | IC50 | = | 107800.0 | nM | - |