Assay Detail
Functional
CHEMBL998457
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Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cucurbitane triterpenoids from Leucopaxillus gentianeus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.09 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507237 | CUCURBITACIN B | — | 1 | 6.11 |
| CHEMBL510964 | LEUCOPAXILLONE A | — | 1 | 5.10 |
| CHEMBL506664 | LEUCOPAXILLONE B | — | 1 | 4.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507237 | CUCURBITACIN B | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL510964 | LEUCOPAXILLONE A | IC50 | = | 7940.0 | nM | 5.10 |
| CHEMBL506664 | LEUCOPAXILLONE B | IC50 | = | 86900.0 | nM | 4.06 |