Assay Detail
Functional
CHEMBL998518
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Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Mycophenolic acid analogs with a modified metabolic profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.39 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL866 | MYCOPHENOLIC ACID | 4.0 | 1 | 5.11 |
| CHEMBL443417 | — | — | 2 | 4.25 |
| CHEMBL487565 | — | — | 1 | 4.15 |
| CHEMBL486325 | — | — | 1 | - |
| CHEMBL444502 | — | — | 1 | - |
| CHEMBL487564 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL866 | MYCOPHENOLIC ACID | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL443417 | — | IC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL487565 | — | IC50 | = | 71000.0 | nM | 4.15 |
| CHEMBL443417 | — | IC50 | = | 88000.0 | nM | 4.06 |
| CHEMBL486325 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL444502 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL487564 | — | IC50 | - | — | - |