Assay Detail
Binding
CHEMBL998524
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Binding affinity to human adenosine A3 receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.38 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL108801 | — | — | 1 | 5.70 |
| CHEMBL111239 | — | — | 1 | 5.68 |
| CHEMBL323042 | — | — | 1 | 5.66 |
| CHEMBL105764 | — | — | 1 | 5.64 |
| CHEMBL109081 | — | — | 1 | 5.34 |
| CHEMBL108374 | — | — | 1 | 4.82 |
| CHEMBL110635 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL108801 | — | Ki | = | 2010.0 | nM | 5.70 |
| CHEMBL111239 | — | Ki | = | 2090.0 | nM | 5.68 |
| CHEMBL323042 | — | Ki | = | 2170.0 | nM | 5.66 |
| CHEMBL105764 | — | Ki | = | 2270.0 | nM | 5.64 |
| CHEMBL109081 | — | Ki | = | 4580.0 | nM | 5.34 |
| CHEMBL108374 | — | Ki | = | 15300.0 | nM | 4.82 |
| CHEMBL110635 | — | Ki | = | 15300.0 | nM | 4.82 |