Compound Detail
CHEMBL101659
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL101659 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NPUWPQJIMKMGDE-OWOJBTEDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
244.2
MW (Da)
2.68
ALogP
4
HBA
4
HBD
80.9
PSA (Ų)
0.61
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosine-protein kinase Lck CHEMBL258 | IC50 | 4.8 | 4.8 | 16000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase Lck | IC50 | = | 16000.0 | nM | 4.8 | Tested in vitro for the inhibition of protein-tyrosine kinase p56lck using angio... | 8411012 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8411012 | 10.1021/jm00072a015 | Tyrosine-protein kinase Lck | 1 |
| - | 10.1007/s00044-009-9236-2 | NON-PROTEIN TARGET | 1 |
| - | 10.1007/s00044-009-9236-2 | Radical scavenging activity | 1 |
Data from ChEMBL 36 via Core Engine