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Compound Detail

CHEMBL106177

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Cl.N=C(N)N/N=C/c1cccc([N+](=O)[O-])c1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL106177
Phase Preclinical
Structure Type MOL
InChI Key FGMOTLLDQDQWIH-HMXKFKBXSA-N
Parent Compound CHEMBL1626710
Active Moiety CHEMBL1626710
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

207.2
MW (Da)
0.41
ALogP
4
HBA
3
HBD
117.4
PSA (Ų)
0.29
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C8H10ClN5O2
MW 243.65
Aromatic Rings 1
Heavy Atoms 15
NP-Likeness -2.00

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
- 10.1016/0960-894X(95)00541-5 Trypanosoma cruzi 1
- 10.1016/0960-894X(95)00541-5 Mus musculus 1
23465801 10.1016/j.bmc.2013.01.051 Glutamate [NMDA] receptor 1

Data from ChEMBL 36 via Core Engine