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Compound Detail

CHEMBL1077744

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CO[C@@H]1OCC2[C@H]1[C@@]1(C)[C@H](O)C[C@@H]3[C@@]4(C)CCCC(C)(C)[C@@H]4CC[C@@]3(C)[C@@H]1C[C@@H]2O

Basic Information

ChEMBL ID CHEMBL1077744
Phase Preclinical
Structure Type MOL
InChI Key PROADJNCLZGCAJ-NDHJQNDDSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

420.6
MW (Da)
4.62
ALogP
4
HBA
2
HBD
58.9
PSA (Ų)
0.65
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H44O4
MW 420.63
Aromatic Rings 0
Heavy Atoms 30
NP-Likeness 3.05

Literature References

PubMed DOI Target Context # Activities
19658408 10.1021/np900326a SK-OV-3 1
19658408 10.1021/np900326a SK-MEL 1
19658408 10.1021/np900326a BT-549 1
19658408 10.1021/np900326a Vero 1
19658408 10.1021/np900326a Staphylococcus aureus 1
19658408 10.1021/np900326a Mycobacterium intracellulare 1

Data from ChEMBL 36 via Core Engine