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Compound Detail

CHEMBL1081702

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COC(=O)C1=C(/C=C(\C(=O)OC)C(C)C)[C@@H]2C[C@H]3C(C)(C)CCC[C@]13C(=O)O2

Basic Information

ChEMBL ID CHEMBL1081702
Phase Preclinical
Structure Type MOL
InChI Key XAZVRXOFQQFDSA-KIBPSTJISA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
16
Publications
0
Known Names

Molecular Properties

390.5
MW (Da)
3.35
ALogP
6
HBA
0
HBD
78.9
PSA (Ų)
0.42
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H30O6
MW 390.48
Aromatic Rings 0
Heavy Atoms 28
NP-Likeness 2.24

Literature References

PubMed DOI Target Context # Activities
19711987 10.1021/np900047p Vero 2
19711987 10.1021/np900047p MCF7 2
19711987 10.1021/np900047p HEp-2 2
19711987 10.1021/np900047p HeLa 2
19711987 10.1021/np900047p Pseudomonas aeruginosa 1
19711987 10.1021/np900047p Proteus mirabilis 1
19711987 10.1021/np900047p Escherichia coli 1
19711987 10.1021/np900047p Mycolicibacterium smegmatis 1
19711987 10.1021/np900047p Candida albicans 1
19711987 10.1021/np900047p Bacillus cereus 1
19711987 10.1021/np900047p Bacillus subtilis 1
19711987 10.1021/np900047p Staphylococcus epidermidis 1
19711987 10.1021/np900047p Staphylococcus aureus 1
19711987 10.1021/np900047p A549 1
19711987 10.1021/np900047p Salmonella 1
19711987 10.1021/np900047p Enterococcus faecalis 1

Data from ChEMBL 36 via Core Engine