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Compound Detail

CHEMBL1087506

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COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)c3ccccc3)cc2)ccc1OC(=O)c1ccccc1

Basic Information

ChEMBL ID CHEMBL1087506
Phase Preclinical
Structure Type MOL
InChI Key YVMBVRZLGDVLTO-PWDIZTEBSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

546.6
MW (Da)
6.39
ALogP
7
HBA
0
HBD
96.0
PSA (Ų)
0.09
QED
2
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C34H26O7
MW 546.58
Aromatic Rings 4
Heavy Atoms 41
NP-Likeness 0.17

Literature References

PubMed DOI Target Context # Activities
20004045 10.1016/j.ejmech.2009.11.035 Trypanosoma brucei brucei 3
20004045 10.1016/j.ejmech.2009.11.035 Leishmania major 1
20004045 10.1016/j.ejmech.2009.11.035 Leishmania mexicana 1
20004045 10.1016/j.ejmech.2009.11.035 HEK293 1

Data from ChEMBL 36 via Core Engine