Compound Detail
CHEMBL1090569
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Basic Information
| ChEMBL ID | CHEMBL1090569 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | INHFGMLOZMSHPE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
466.0
MW (Da)
6.54
ALogP
2
HBA
0
HBD
37.4
PSA (Ų)
0.31
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Oxysterols receptor LXR-beta CHEMBL4093 | IC50 | 5.5 | 5.5 | 3162.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Oxysterols receptor LXR-beta | IC50 | = | 3162.28 | nM | 5.5 | Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 h... | 20345102 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20345102 | 10.1021/jm901797p | Oxysterols receptor LXR-beta | 1 |
Data from ChEMBL 36 via Core Engine