Compound Detail
CHEMBL1095280
ERITADENINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1095280 |
| Name | ERITADENINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LIEMBEWXEZJEEZ-INEUFUBQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
13
Publications
0
Known Names
Molecular Properties
253.2
MW (Da)
-1.79
ALogP
8
HBA
4
HBD
147.4
PSA (Ų)
0.50
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Adenosylhomocysteinase CHEMBL3118 | IC50 | 7.52 | 7.52 | 30.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Adenosylhomocysteinase | IC50 | = | 30.0 | nM | 7.52 | Inhibition of S-adenosyl-L-homocysteine hydrolase in intact rat hepatocytes | 19692248 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19692248 | 10.1016/j.bmc.2009.07.061 | Adenosylhomocysteinase | 1 |
| - | 10.6019/CHEMBL3832761 | Cryptosporidium parvum | 1 |
| - | 10.6019/CHEMBL3832761 | HepG2 | 1 |
| - | 10.6019/CHEMBL3987221 | Ferrochelatase, mitochondrial | 1 |
| - | 10.6019/CHEMBL3987221 | Porphobilinogen deaminase | 1 |
| - | 10.6019/CHEMBL4513101 | Naegleria gruberi | 1 |
| - | 10.6019/CHEMBL4513149 | Candida albicans | 1 |
| - | 10.6019/CHEMBL4513149 | Cryptococcus neoformans | 1 |
| - | 10.6019/CHEMBL4513149 | Escherichia coli | 1 |
| - | 10.6019/CHEMBL4513149 | Klebsiella pneumoniae | 1 |
| - | 10.6019/CHEMBL4513149 | Pseudomonas aeruginosa | 1 |
| - | 10.6019/CHEMBL4513149 | Acinetobacter baumannii | 1 |
| - | 10.6019/CHEMBL4513149 | Staphylococcus aureus | 1 |
Data from ChEMBL 36 via Core Engine