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Compound Detail

CHEMBL1095699

AZASERINE
🧪 Phase II
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🧪 Phase II
[N-]=[N+]=CC(=O)OC[C@H](N)C(=O)O

Basic Information

ChEMBL ID CHEMBL1095699
Name AZASERINE
Phase Phase II
Structure Type MOL
InChI Key MZZGOOYMKKIOOX-VKHMYHEASA-N

Known Names

Azaserina Azaserine CL 337 CL-337 CN-15,757 CN-15757 L-serine, diazoacetate (ester) NSC-742 P-165
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
11
Publications
9
Known Names

Molecular Properties

173.1
MW (Da)
-1.76
ALogP
4
HBA
2
HBD
126.0
PSA (Ų)
0.23
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Single Enantiomer

Flags

Natural Product
USAN Year 1968

Extended Properties

Molecular Formula C5H7N3O4
MW 173.13
Aromatic Rings 0
Heavy Atoms 12
NP-Likeness 1.07

Literature References

PubMed DOI Target Context # Activities
18794383 10.1128/aac.01648-07 Saccharomyces cerevisiae 12
18794383 10.1128/aac.01648-07 Candida albicans 5
20133022 10.1016/j.ejmech.2010.01.008 NON-PROTEIN TARGET 2
18834112 10.1021/jm800656v Amine oxidase [flavin-containing] A 1
18834112 10.1021/jm800656v Amine oxidase [flavin-containing] B 1
17428028 10.1021/ci6004542 Phospholipidosis 1
20799726 10.1021/mp100103e Phospholipidosis 1
20553011 10.1021/tx1000865 Hepatotoxicity 1
20843939 10.1124/dmd.110.035113 Hepatotoxicity 1
23571415 10.1124/mol.112.084152 Solute carrier organic anion transporter family member 1B1 1
23571415 10.1124/mol.112.084152 Solute carrier organic anion transporter family member 1B3 1

Data from ChEMBL 36 via Core Engine