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Compound Detail

CHEMBL109652

SYRINGOL
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COc1cccc(OC)c1O

Basic Information

ChEMBL ID CHEMBL109652
Name SYRINGOL
Phase Preclinical
Structure Type MOL
InChI Key KLIDCXVFHGNTTM-UHFFFAOYSA-N
0
Targets
3
Activities
1
Assay Types
0
PK Parameters
12
Publications
0
Known Names

Molecular Properties

154.2
MW (Da)
1.41
ALogP
3
HBA
1
HBD
38.7
PSA (Ų)
0.70
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C8H10O3
MW 154.16
Aromatic Rings 1
Heavy Atoms 11
NP-Likeness 0.33

Activity Summary

EC50 3 meas.

Literature References

PubMed DOI Target Context # Activities
- 10.1016/j.cropro.2012.09.015 Lasiodiplodia theobromae 5
- 10.1016/j.cropro.2012.09.015 Botryosphaeria dothidea 4
- 10.1016/j.cropro.2012.09.015 Neofusicoccum ribis 4
- 10.1016/j.cropro.2012.09.015 Diplodia seriata 3
- 10.6019/CHEMBL3988442 Unchecked 3
12109905 10.1021/jm010461a GABA-A receptor; alpha-1/beta-2/gamma-2 2
16279782 10.1021/jm050567w L1210 2
- 10.6019/CHEMBL4513160 Pseudomonas aeruginosa 2
11606122 10.1021/jm010903i Mus musculus 1
12109905 10.1021/jm010461a Xenopus laevis 1
12109905 10.1021/jm010461a No relevant target 1
- 10.6019/CHEMBL4513160 Acinetobacter baumannii 1

Data from ChEMBL 36 via Core Engine