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Compound Detail

CHEMBL1098319

2-MERCAPTOETHANESULFONIC ACID
💊 Approved Drug
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💊 Approved Drug

Basic Information

ChEMBL ID CHEMBL1098319
Name 2-MERCAPTOETHANESULFONIC ACID
Phase Approved
Structure Type MOL
InChI Key ZNEWHQLOPFWXOF-UHFFFAOYSA-N
Therapeutic ✓ Yes

Known Names

2-mercaptoethanesulfonic acid Coenzyme m Mesna free acid
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
20
Publications
3
Known Names

Molecular Properties

142.2
MW (Da)
-0.20
ALogP
3
HBA
2
HBD
54.4
PSA (Ų)
0.41
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
First Approval 1988
Availability Prescription
Chirality Achiral

Routes of Administration

Oral Parenteral

Flags

Natural Product
USAN Year 1990

Extended Properties

Molecular Formula C2H6O3S2
MW 142.20
Aromatic Rings 0
Heavy Atoms 7
NP-Likeness 0.01

Drug Warnings

Withdrawn
immune system toxicity
hypersensitivity reactions of different degrees, including slight skin eruptions up to more serious anaphylactic reactions, in patients with autoimmune conditions.
Country: Germany   Year: 1991
Withdrawn
immune system toxicity
hypersensitivity reactions of different degrees, including slight skin eruptions up to more serious anaphylactic reactions, in patients with autoimmune conditions.
Country: Germany   Year: 1991
Withdrawn
immune system toxicity
hypersensitivity reactions of different degrees, including slight skin eruptions up to more serious anaphylactic reactions, in patients with autoimmune conditions.
Country: Germany   Year: 1991
Withdrawn
immune system toxicity
hypersensitivity reactions of different degrees, including slight skin eruptions up to more serious anaphylactic reactions, in patients with autoimmune conditions.
Country: Germany   Year: 1991

Literature References

PubMed DOI Target Context # Activities
- 10.6019/CHEMBL4808148 Histone deacetylase 6 2
37468498 10.1038/s41467-023-40064-9 Prostaglandin G/H synthase 1 2
37468498 10.1038/s41467-023-40064-9 Alpha-1A adrenergic receptor 2
37468498 10.1038/s41467-023-40064-9 Thromboxane A2 receptor 2
37468498 10.1038/s41467-023-40064-9 Muscarinic acetylcholine receptor M1 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
37468498 10.1038/s41467-023-40064-9 Estrogen receptor 1
37468498 10.1038/s41467-023-40064-9 Acetylcholinesterase 1
37468498 10.1038/s41467-023-40064-9 Sodium-dependent noradrenaline transporter 1
37468498 10.1038/s41467-023-40064-9 Sodium-dependent serotonin transporter 1
38318365 10.1016/j.isci.2024.108907 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1
37468498 10.1038/s41467-023-40064-9 Mu-type opioid receptor 1
37468498 10.1038/s41467-023-40064-9 Amine oxidase [flavin-containing] A 1
37468498 10.1038/s41467-023-40064-9 5-hydroxytryptamine receptor 1A 1
37468498 10.1038/s41467-023-40064-9 Vascular endothelial growth factor receptor 2 1
37468498 10.1038/s41467-023-40064-9 cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A 1
37468498 10.1038/s41467-023-40064-9 Sodium-dependent dopamine transporter 1
37468498 10.1038/s41467-023-40064-9 Muscarinic acetylcholine receptor M2 1
37468498 10.1038/s41467-023-40064-9 Prothrombin 1
37468498 10.1038/s41467-023-40064-9 Voltage-gated inwardly rectifying potassium channel KCNH2 1

Data from ChEMBL 36 via Core Engine