Compound Detail
CHEMBL1099252
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1099252 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UDUUMRSWVRLVHM-VZUCSPMQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
236.3
MW (Da)
1.46
ALogP
4
HBA
2
HBD
63.3
PSA (Ų)
0.47
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HeLa CHEMBL399 | IC50 | 5.27 | 5.27 | 5350.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HeLa | IC50 | = | 5350.0 | nM | 5.27 | Antiproliferative activity against human HeLa cells after 72 hrs by sulforhodami... | 20353152 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20353152 | 10.1021/jm9014394 | HT-29 | 1 |
| 20353152 | 10.1021/jm9014394 | SGC-7901 | 1 |
| 20353152 | 10.1021/jm9014394 | HL-60 | 1 |
| 20353152 | 10.1021/jm9014394 | HeLa | 1 |
| 20353152 | 10.1021/jm9014394 | DNA topoisomerase 2-alpha | 1 |
Data from ChEMBL 36 via Core Engine