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Compound Detail

CHEMBL1173474

BEHENIC ACID
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CCCCCCCCCCCCCCCCCCCCCC(=O)O

Basic Information

ChEMBL ID CHEMBL1173474
Name BEHENIC ACID
Phase Preclinical
Structure Type MOL
InChI Key UKMSUNONTOPOIO-UHFFFAOYSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
17
Publications
0
Known Names

Molecular Properties

340.6
MW (Da)
7.89
ALogP
1
HBA
1
HBD
37.3
PSA (Ų)
0.23
QED
1
Ro5 Violations
20
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C22H44O2
MW 340.59
Aromatic Rings 0
Heavy Atoms 24
NP-Likeness 0.29

Activity Summary

IC50 3 meas. best 4.52

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Peroxisome proliferator-activated receptor gamma
CHEMBL235
IC50 4.52 4.52 30000.0 1
Peroxisome proliferator-activated receptor alpha
CHEMBL239
IC50 4.52 4.52 30000.0 1
Peroxisome proliferator-activated receptor delta
CHEMBL3979
IC50 4.52 4.52 30000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
- 10.6019/CHEMBL4808148 Histone deacetylase 6 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
30220607 10.1016/j.bmcl.2018.09.013 Acetylcholinesterase 2
- 10.1007/s00044-012-0285-6 Peroxisome proliferator-activated receptor alpha 1
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 1
- 10.21203/rs.3.rs-23951/v1 SARS-CoV-2 1
30220607 10.1016/j.bmcl.2018.09.013 Cholinesterase 1
24360558 10.1016/j.bmcl.2013.12.008 Cortical neurone 1
20565070 10.1021/np1000945 NON-PROTEIN TARGET 1
- 10.1007/s00044-012-0285-6 Peroxisome proliferator-activated receptor gamma 1
- 10.1007/s00044-012-0285-6 Peroxisome proliferator-activated receptor delta 1
21813280 10.1016/j.bmc.2011.07.006 Escherichia coli 1
21813280 10.1016/j.bmc.2011.07.006 Candida albicans 1
21813280 10.1016/j.bmc.2011.07.006 Pseudomonas aeruginosa 1
21813280 10.1016/j.bmc.2011.07.006 Bacillus subtilis 1
21813280 10.1016/j.bmc.2011.07.006 Staphylococcus aureus 1

Data from ChEMBL 36 via Core Engine