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Compound Detail

CHEMBL1189025

BROSTALLICIN
🧪 Phase II
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🧪 Phase II
C=C(Br)C(=O)Nc1cc(C(=O)Nc2cc(C(=O)Nc3cc(C(=O)Nc4cc(C(=O)NCCNC(=N)N)n(C)c4)n(C)c3)n(C)c2)n(C)c1

Basic Information

ChEMBL ID CHEMBL1189025
Name BROSTALLICIN
Phase Phase II
Structure Type MOL
InChI Key RXOVOXFAAGIKDQ-UHFFFAOYSA-N

Known Names

Brostalicina Brostallicin Brostallicine
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
3
Known Names
3
Indications
1
Mechanisms

Molecular Properties

723.6
MW (Da)
1.86
ALogP
10
HBA
8
HBD
227.1
PSA (Ų)
0.05
QED
2
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral

Flags

Natural Product

Extended Properties

Molecular Formula C30H35BrN12O5
MW 723.59
Aromatic Rings 4
Heavy Atoms 48
NP-Likeness -0.36

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
DNA disrupting agent DISRUPTING AGENT DNA

Indications

Liposarcoma, Myxoid Triple Negative Breast Neoplasms Multiple Myeloma

Data from ChEMBL 36 via Core Engine