Compound Detail
CHEMBL119870
PHENAZINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL119870 |
| Name | PHENAZINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PCNDJXKNXGMECE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
180.2
MW (Da)
2.78
ALogP
2
HBA
0
HBD
25.8
PSA (Ų)
0.50
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HepG2 CHEMBL395 | IC50 | 5.11 | 5.11 | 7800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HepG2 | IC50 | = | 7800.0 | nM | 5.11 | Cytotoxicity against human HepG2 cells after 48 hrs by BrDU-incorporation based ... | 30684866 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1271403 | 10.1021/jm00227a008 | No relevant target | 2 |
| 12904059 | 10.1021/jm034093h | Major prion protein | 1 |
| 19056282 | 10.1016/j.bmc.2008.11.040 | ADMET | 1 |
| 30684866 | 10.1016/j.ejmech.2019.01.028 | HepG2 | 1 |
| 30951303 | 10.1021/acs.jmedchem.9b00370 | Staphylococcus aureus | 1 |
| 30951303 | 10.1021/acs.jmedchem.9b00370 | Staphylococcus epidermidis | 1 |
Data from ChEMBL 36 via Core Engine