Compound Detail
CHEMBL1212975
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1212975 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XEKNACRTWJHOCE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
204.2
MW (Da)
2.10
ALogP
2
HBA
2
HBD
48.6
PSA (Ų)
0.70
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Taste receptor type 2 member 38 CHEMBL4523248 | EC50 | 6.3 | 6.3 | 500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Taste receptor type 2 member 38 | EC50 | = | 500.0 | nM | 6.3 | Activity at human TAS2R38 expressed in HEK-293T-Galpha16-gustducin44 cells asses... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18176557 | 10.1038/nchembio.63 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine