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Compound Detail

CHEMBL121622

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O=C1c2ccccc2-c2c1c1ccccc1c(=O)n2CCCO

Basic Information

ChEMBL ID CHEMBL121622
Phase Preclinical
Structure Type MOL
InChI Key AEVCRSQXDKOUMY-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
20
Publications
0
Known Names

Molecular Properties

305.3
MW (Da)
2.60
ALogP
4
HBA
1
HBD
59.3
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C19H15NO3
MW 305.33
Aromatic Rings 3
Heavy Atoms 23
NP-Likeness 0.15

Literature References

PubMed DOI Target Context # Activities
23472886 10.1021/jm400026k Retinoic acid receptor RXR-alpha 3
15509164 10.1021/jm040025z HOP-62 1
15509164 10.1021/jm040025z Panel (Carcinoma cell lines) 1
15509164 10.1021/jm040025z MDA-MB-435 1
15509164 10.1021/jm040025z DU-145 1
15509164 10.1021/jm040025z SN12C 1
15509164 10.1021/jm040025z OVCAR-3 1
15509164 10.1021/jm040025z UACC-62 1
15509164 10.1021/jm040025z NON-PROTEIN TARGET 1
15509164 10.1021/jm040025z HCT-116 1
15509164 10.1021/jm040025z DNA topoisomerase 1 1
11020283 10.1021/jm000029d HOP-62 1
11020283 10.1021/jm000029d DNA topoisomerase 1 1
11020283 10.1021/jm000029d Panel (Carcinoma cell lines) 1
11020283 10.1021/jm000029d MDA-MB-435 1
11020283 10.1021/jm000029d DU-145 1
11020283 10.1021/jm000029d SN12C 1
11020283 10.1021/jm000029d OVCAR-3 1
11020283 10.1021/jm000029d UACC-62 1
11020283 10.1021/jm000029d SF-539 1

Data from ChEMBL 36 via Core Engine