Compound Detail
CHEMBL12214
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Basic Information
| ChEMBL ID | CHEMBL12214 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MNOILHPDHOHILI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
132.2
MW (Da)
0.39
ALogP
1
HBA
0
HBD
6.5
PSA (Ų)
0.44
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Taste receptor type 2 member 38 CHEMBL4523248 | EC50 | 4.0 | 4.0 | 100000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Taste receptor type 2 member 38 | EC50 | = | 100000.0 | nM | 4.0 | Activity at human TAS2R38 expressed in HEK-293T-Galpha16-gustducin44 cells asses... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6793727 | 10.1021/jm00141a015 | Friend leukemia cell line | 3 |
Data from ChEMBL 36 via Core Engine