Compound Detail
CHEMBL122523
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C=C(c1ccc(OCCc2ccccc2)c(OC)c1)[C@H]1CN[C@H](C(=O)O)[C@H]1CC(=O)O
Basic Information
| ChEMBL ID | CHEMBL122523 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OAQJMDPTQVJPML-YYDVJCTNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
425.5
MW (Da)
3.09
ALogP
5
HBA
3
HBD
105.1
PSA (Ų)
0.54
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, kainate 2 CHEMBL3683 | Ki | 5.89 | 5.89 | 1284.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, kainate 2 | Ki | = | 1284.0 | nM | 5.89 | Inhibition of [3H]kainate binding at ionotropic glutamate receptor kainate 2 | 8809152 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8809152 | 10.1021/jm960155a | Glutamate receptor ionotropic, kainate 2 | 4 |
Data from ChEMBL 36 via Core Engine