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Compound Detail

CHEMBL1229950

2-ALLYLPHENOL
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Basic Information

ChEMBL ID CHEMBL1229950
Name 2-ALLYLPHENOL
Phase Preclinical
Structure Type MOL
InChI Key QIRNGVVZBINFMX-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

134.2
MW (Da)
2.12
ALogP
1
HBA
1
HBD
20.2
PSA (Ų)
0.61
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C9H10O
MW 134.18
Aromatic Rings 1
Heavy Atoms 10
NP-Likeness 0.84

Activity Summary

Kd 1 meas. best 4.14

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Endolysin
CHEMBL5206
Kd 4.14 4.14 72000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Endolysin Kd = 72000.0 nM 4.14 Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102H double mutant ex... 23473072

Literature References

PubMed DOI Target Context # Activities
19685448 10.1002/ps.1820 Botrytis cinerea 16
19685448 10.1002/ps.1820 Pyricularia grisea 4
23473072 10.1021/jm301823g Endolysin 2
- 10.1016/j.cropro.2007.02.007 Alternaria solani 1
- 10.1016/j.cropro.2007.02.007 Fulvia fulva 1
- 10.1016/j.cropro.2007.02.007 Botrytis cinerea 1

Data from ChEMBL 36 via Core Engine