Compound Detail
CHEMBL123376
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Basic Information
| ChEMBL ID | CHEMBL123376 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VLZBRVJVCCNPRJ-VQAUAJGESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
353.4
MW (Da)
2.82
ALogP
4
HBA
3
HBD
109.8
PSA (Ų)
0.76
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.07 | 5.725 | 860.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 860.0 | nM | 6.07 | Binding affinity for Group II Metabotropic glutamate receptor was measured using... | 9464367 |
| Unchecked | IC50 | = | 4200.0 | nM | 5.38 | Binding affinity for Group II Metabotropic glutamate receptor was measured using... | 9464367 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9464367 | 10.1021/jm970498o | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine