Compound Detail
CHEMBL1233987
DIAMINOPYRIMIDINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1233987 |
| Name | DIAMINOPYRIMIDINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YAAWASYJIRZXSZ-UHFFFAOYSA-N |
1
Targets
4
Activities
2
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
110.1
MW (Da)
-0.36
ALogP
4
HBA
2
HBD
77.8
PSA (Ų)
0.48
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas.
Kd 1 meas. best 4.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RNA CHEMBL2311222 | Kd | 4.1 | 4.1 | 80000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RNA | Kd | = | 80000.0 | nM | 4.1 | Binding affinity to RNA (unknown origin) by fluorescence based analysis | 37186875 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32658475 | 10.1021/acs.jmedchem.0c00546 | Unchecked | 4 |
| 20606069 | 10.1128/aac.00361-10 | Staphylococcus aureus | 2 |
| 32658475 | 10.1021/acs.jmedchem.0c00546 | Dihydrofolate reductase | 1 |
| 37186875 | 10.1021/acs.jmedchem.3c00034 | RNA | 1 |
Data from ChEMBL 36 via Core Engine