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Compound Detail

CHEMBL1235429

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CC(=O)O[C@@]12[C@H](O)[C@@H](C)[C@@]3(O)[C@@H](C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@@H]1C2(C)C

Basic Information

ChEMBL ID CHEMBL1235429
Phase Preclinical
Structure Type MOL
InChI Key SDSVJYOOAPRSDA-RPCQODIISA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

406.5
MW (Da)
0.50
ALogP
7
HBA
4
HBD
124.3
PSA (Ų)
0.39
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C22H30O7
MW 406.48
Aromatic Rings 0
Heavy Atoms 29
NP-Likeness 3.30

Activity Summary

EC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
25970561 10.1021/acs.jnatprod.5b00073 Unchecked 3
25970561 10.1021/acs.jnatprod.5b00073 Human immunodeficiency virus 2 1
25970561 10.1021/acs.jnatprod.5b00073 NON-PROTEIN TARGET 1
25970561 10.1021/acs.jnatprod.5b00073 Human immunodeficiency virus 1 1
28383891 10.1021/acs.jnatprod.6b00786 Mycolicibacterium smegmatis 1

Data from ChEMBL 36 via Core Engine