Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL124682

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1cn([C@@H]2O[C@H](CO)[C@@H](CN)[C@H]2O)c(=O)[nH]c1=O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL124682
Phase Preclinical
Structure Type MOL
InChI Key JYDMCTQCWURNLL-FDDDBJFASA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

271.3
MW (Da)
-2.33
ALogP
7
HBA
4
HBD
130.6
PSA (Ų)
0.49
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H17N3O5
MW 271.27
Aromatic Rings 1
Heavy Atoms 19
NP-Likeness 1.16

Activity Summary

Ki 2 meas.

Literature References

PubMed DOI Target Context # Activities
12930144 10.1021/jm021108n Thymidylate kinase 1
12930144 10.1021/jm021108n Thymidine kinase, cytosolic 1
12930144 10.1021/jm021108n Unchecked 1
8381182 10.1021/jm00055a006 L1210 1
8381182 10.1021/jm00055a006 P388 1
8381182 10.1021/jm00055a006 Unchecked 1
8381182 10.1021/jm00055a006 CCRF-CEM 1

Data from ChEMBL 36 via Core Engine