Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1254095

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CN(c1ccc(NC(=O)Nc2cccc(C(F)(F)F)c2)cc1)c1ncnc2ccn(C)c12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1254095
Phase Preclinical
Structure Type MOL
InChI Key MNSYGLMJOPPFTK-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

440.4
MW (Da)
5.40
ALogP
5
HBA
2
HBD
75.1
PSA (Ų)
0.45
QED
1
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H19F3N6O
MW 440.43
Aromatic Rings 4
Heavy Atoms 32
NP-Likeness -1.44

Literature References

PubMed DOI Target Context # Activities
20833055 10.1016/j.bmc.2010.08.017 Vascular endothelial growth factor receptor 2 1
20833055 10.1016/j.bmc.2010.08.017 HUVEC 1

Data from ChEMBL 36 via Core Engine