Compound Detail
CHEMBL1255971
IMMUCILLIN A Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1255971 |
| Name | IMMUCILLIN A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AMFDITJFBUXZQN-YNFHYIOASA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
265.3
MW (Da)
-1.73
ALogP
7
HBA
6
HBD
140.3
PSA (Ų)
0.38
QED
1
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 9.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 9.05 | 8.54 | 0.9 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 0.9 | nM | 9.05 | Inhibition of Trypanosoma brucei brucei inosine-adenosine-guanosine nucleoside h... | 20194690 |
| Unchecked | Ki | = | 4.4 | nM | 8.36 | Inhibition of Trypanosoma brucei brucei Inosine guanosine nucleoside hydrolase | 20194690 |
| Unchecked | Ki | = | 6.2 | nM | 8.21 | Inhibition of Trypanosoma vivax Inosine-adenosine-guanosine-nucleoside hydrolase | 20194690 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20194690 | 10.1128/aac.01787-09 | Unchecked | 4 |
| 20194690 | 10.1128/aac.01787-09 | Trypanosoma brucei brucei | 1 |
| 20194690 | 10.1128/aac.01787-09 | ADMET | 1 |
| 20194690 | 10.1128/aac.01787-09 | Trypanosoma cruzi | 1 |
| 20194690 | 10.1128/aac.01787-09 | Leishmania infantum | 1 |
| 20194690 | 10.1128/aac.01787-09 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine