Compound Detail
CHEMBL127232
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL127232 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VXKXFPCXSPRMGE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
266.4
MW (Da)
1.55
ALogP
4
HBA
0
HBD
42.3
PSA (Ų)
0.84
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 CHEMBL3371 | Ki | 6.21 | 6.21 | 620.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 | Ki | = | 620.0 | nM | 6.21 | Binding affinity as displacement of [3H]5-HT binding to 5-hydroxytryptamine 6 re... | 11689074 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11689074 | 10.1021/jm010943m | 5-hydroxytryptamine receptor 6 | 1 |
Data from ChEMBL 36 via Core Engine