Compound Detail
CHEMBL127734
CARCAINIUM CHLORIDE 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL127734 |
| Name | CARCAINIUM CHLORIDE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | YGCONRRHHMKQRL-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1180484 |
| Active Moiety | CHEMBL1180484 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
5
Known Names
Molecular Properties
312.4
MW (Da)
2.34
ALogP
2
HBA
2
HBD
58.2
PSA (Ų)
0.80
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 1 meas. best 5.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sodium channel alpha subunits; brain (Types I, II, III) CHEMBL2096682 | IC50 | 5.41 | 5.41 | 3900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sodium channel alpha subunits; brain (Types I, II, III) | IC50 | = | 3900.0 | nM | 5.41 | Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on vol... | 2579237 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2579237 | 10.1021/jm00381a019 | Sodium channel alpha subunits; brain (Types I, II, III) | 2 |
| 24332655 | 10.1016/j.bmc.2013.11.049 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine