Compound Detail
CHEMBL130497
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Basic Information
| ChEMBL ID | CHEMBL130497 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KMRHMPLKDOCESH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
255.4
MW (Da)
4.02
ALogP
1
HBA
1
HBD
26.0
PSA (Ų)
0.85
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate [NMDA] receptor CHEMBL2094124 | Ki | 5.39 | 5.39 | 4080.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate [NMDA] receptor | Ki | = | 4080.0 | nM | 5.39 | The compound was tested for its ability to block PCP N-methyl-D-aspartate glutam... | 9464369 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9464369 | 10.1021/jm9704412 | Glutamate [NMDA] receptor | 1 |
Data from ChEMBL 36 via Core Engine