Compound Detail
CHEMBL131840
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Basic Information
| ChEMBL ID | CHEMBL131840 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KRFOYOCNRILWAO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
209.7
MW (Da)
1.85
ALogP
3
HBA
0
HBD
29.0
PSA (Ų)
0.71
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.56
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 CHEMBL276 | IC50 | 6.56 | 6.56 | 276.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | IC50 | = | 276.0 | nM | 6.56 | Displacement of [3H]oxotremorine-M (Oxo-M) from rat hippocampus muscarinic acety... | 1433209 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1433209 | 10.1021/jm00100a005 | Muscarinic acetylcholine receptor M1 | 3 |
Data from ChEMBL 36 via Core Engine