Compound Detail
CHEMBL1370907
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Basic Information
| ChEMBL ID | CHEMBL1370907 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DLNCASBDPGAELF-UHFFFAOYSA-N |
3
Targets
4
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
295.4
MW (Da)
3.45
ALogP
4
HBA
1
HBD
58.6
PSA (Ų)
0.58
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.24
IC50 1 meas. best 4.32
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 5.24 | 5.03 | 5825.0 | 2 |
| H4 CHEMBL1075452 | EC50 | 5.21 | 5.21 | 6225.0 | 1 |
| Leucine aminopeptidase CHEMBL1293313 | IC50 | 4.32 | 4.32 | 47490.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 5825.0 | nM | 5.24 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Activato... | - |
| H4 | EC50 | = | 6225.0 | nM | 5.21 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Activato... | - |
| Unchecked | EC50 | = | 15272.0 | nM | 4.82 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Acti... | - |
| Leucine aminopeptidase | IC50 | = | 47490.0 | nM | 4.32 | PUBCHEM_BIOASSAY: Inhibitors of Plasmodium falciparum M17- Family Leucine Aminop... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33756127 | 10.1016/j.ejmech.2021.113326 | DCN1-like protein 1 | 2 |
Data from ChEMBL 36 via Core Engine