Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL137813

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
N#C/C(=C\c1cccc(O)c1)C(N)=O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL137813
Phase Preclinical
Structure Type MOL
InChI Key QNEGNWNZPWHAKM-XBXARRHUSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

188.2
MW (Da)
0.78
ALogP
3
HBA
2
HBD
87.1
PSA (Ų)
0.53
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H8N2O2
MW 188.19
Aromatic Rings 1
Heavy Atoms 14
NP-Likeness -0.15

Activity Summary

IC50 2 meas.

Literature References

PubMed DOI Target Context # Activities
8474097 10.1021/jm00056a001 Tyrosine-protein kinase Lck 2
22094280 10.1016/j.bmc.2011.10.061 Unchecked 2
22094280 10.1016/j.bmc.2011.10.061 Prothrombin 1

Data from ChEMBL 36 via Core Engine